Cardiology is flow.

نویسندگان

  • Yoram Richter
  • Elazer R Edelman
چکیده

Cardiology is about flow. The primary purpose of the cardiovascular system is to drive, control, and maintain blood flow to all parts of the body. Flow dictates the form and function of the heart and blood vessels through ontogenic and phylogenic development, the structural and functional consequence of repair, and in its end stages, remodeling and response to failure. Flow should therefore be a primary focus by which we explain where lesions form, why they degrade and decompensate, and how we grade the extent of restoration of function after vascular intervention. Yet this is not the case. Flow is not a standard part of our clinical lexicon. Few reliable and consistent means of measuring flow exist. Despite early use of surrogate flow markers (eg, TIMI frame count), we do not quantify flow restoration after interventions. Moreover, there is simply no agreement as to the aspect or degree of flow that is most important in lesion development or functional recovery.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cor Triatriatum Sinistrum Presenting as Cyanotic Congenital Heart Disease A Rare Case Report

  Cor triatriatum is an acyanotic congenital heart disease. We present a rare case of cor triatriatum sinistrum in a 6-month-old female infant who was presented with cyanosis and failure to thrive. The 2D transthoracic echocardiography and the Doppler color flow imaging showed a proximal venous chamber communicating to the distal left atrium  through restrictive opening to the low-pressure, dis...

متن کامل

Correlation between serum levels of cystatin C and coronary slow flow and body mass index in men

Background: Cystatin C (Cys C) as a cysteine protease inhibitor is produced in a constant level from all nucleated cells. The purpose of this study was to investigate the correlation between serum levels of Cys C and coronary slow flow (CSF) and body mass index (BMI) in men. Methods: This investigation is in the form of a descriptive-analytical study. The statistical population was all non-act...

متن کامل

Serial Myocardial Imaging after a Single Dose of Thallium-201

Although thallium-201 exercise scintigraphy has been established for the detection of myocardial ischemia and viability, little is known regarding the myocardial thallium-201 kinetics during angioplasty. Herein, we report a 77-year old man with angina pectoris, in whom serial myocardial imaging after a single dose of thallium-201 was helpful in identifying not only the culprit lesion and myocar...

متن کامل

Noninvasive measurements of myocardial oxygen consumption--can we do better?

Normal cardiac performance reflects the interdependence between myocardial mechanical function, myocardial oxygen consumption (MVO2), and blood flow. Indeed, physiologic processes directly associated with systolic function (e.g., wall stress, shortening, heart rate, contractility) are major determinants of MVO2. Conversely, when myocardial blood flow is interrupted, there is rapid cessation of ...

متن کامل

Systolic ejection murmurs in the era of modern cardiology: what do we really know?

The basics of pulsatile ejection dynamics are reviewed in order to clarify the relationships among left ventricular and aortic pressures, intra-left ventricular and aortic flow velocities, and cardiovascular sound. The principles of turbulent flow are examined using the Reynolds number concept, and the evidence for cause-and-effect relationships between turbulent flow and murmur generation is p...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation

دوره 113 23  شماره 

صفحات  -

تاریخ انتشار 2006